{\rtf1\deflang1033\deflangfe1033\margl720\margr720\margt360\margb360{\stylesheet{\fs20\lang1033\snext0 Normal;} {\s1\sb240\keepn{\*\pn \pnlvl1\pndec\pnprev1\pnstart1\pnsp144}\b\f0\fs30\lang1033 \sbasedon0\snext0 heading 1;} {\s2\sb200\keepn{\*\pn \pnlvl2\pndec\pnprev1\pnstart1\pnsp144{\pntxtb.}}\b\f0\fs26\lang1033 \sbasedon0\snext0 heading 2;} {\s3\sb180\keepn{\*\pn \pnlvl3\pndec\pnprev1\pnstart1\pnsp144{\pntxtb.}}\b\f0\fs22\lang1033 \sbasedon0\snext0 heading 3;} {\s4\sb160\keepn{\*\pn \pnlvl4\pnucltr\pnprev1\pnstart1\pnsp144{\pntxtb.}}\b\f0\fs22\lang1033 \sbasedon0\snext0 heading 4;} {\s5\sb140\keepn{\*\pn \pnlvl5\pncltr\pnprev1\pnstart1\pnsp144}\b\f0\fs20\lang1033 \sbasedon0\snext0 heading 5;} {\s6\tqc\lang1033\sbasedon0\snext6 footer;} {\*\cs16 \additive\super\sbasedon10 footnote reference;} {\*\cs18 \additive\sbasedon10 page number;}} {\fonttbl{\f0\fnil Times New Roman;}{\f1\fnil Courier New}{\f2005\fnil Courier New;}{\f2010\fnil Wingdings;}{\f2020\fnil Webdings;}{\f2\fnil Arial;}{\f3\fnil Arial;}{\f4\fnil LucidaHandwriting;}{\f5\fnil Symbol;}{\f6\fnil Symbol;}{\f7\fnil Ferdsch;}{\f30\fnil Myriad Cn Semibold;}{\f31\fnil Myriad Roman;}{\f50\fnil Courier New;}{\f51\fnil Times New Roman;}{\f52\fnil Arial;}{\f53\fnil Symbol;}{\f54\fnil Wingdings;}{\f55\fnil Wingdings 2;}{\f56\fnil Wingdings 3;}{\f57\fnil Webdings;}{\f58\fnil Arial Narrow;}{\f59\fnil Arial Unicode MS;}{\f60\fnil Cyberbit;}{\f61\fnil Morningstar 1U Light;}{\f62\fnil Calibri;}} {\colortbl;\red0\green0\blue0;\red127\green0\blue0;\red0\green0\blue255;\red127\green127\blue127;\red0\green51\blue153;\red255\green204\blue0;\red255\green255\blue255;\red246\green244\blue236;\red0\green0\blue0;} {\*\bkmkstart filing_1}{\*\bkmkend filing_1}{\*\bkmkstart doc_1_1}{\*\bkmkend doc_1_1}\par\pard\plain\cf1\f51\fs20\qr Filed by Akebia Therapeutics, Inc.\par\pard\plain\cf1\f51\fs20\qr Pursuant to Rule 425 under the Securities Act of 1933\par\pard\plain\cf1\f51\fs20\qr Commission File No.: 001-36352\par\pard\plain\sb264\cf1\f51\fs20\qr Subject Company: Keryx Biopahrmaceuticals, Inc.\par\pard\plain\cf1\f51\fs20\qr Commission File No.: 000-30929\par\pard\plain\cf1\f51\fs20\qr Date: June\~28, 2018\par\pard\plain\sb264\cf1\f51\fs20\ql The following are social media communications by Akebia Therapeutics, Inc. (\u8220?Akebia\u8221?) that discuss the proposed\plain\cf1\f51\fs20\ql merger of Akebia and Keryx Biopharmaceuticals, Inc.\par\pard\plain\cf1\f51\fs24\ql \~\par\pard\plain\brdrb\brdrs\sa44\cf1\f51\fs20\ql \~\par\pard\plain\sb264\cf1\f51\fs20\b\i\qc Social Media Communications by Akebia\par\pard\plain\sb264\cf1\f51\fs20\ql The following communication was posted on June\~28, 2018 by Akebia on Twitter:\par\pard\plain\cf1\f51\fs24\ql \~\par\ql{\*\shppict{\pict\pngblip\picw394\pich217\picscalex75\picscaley75\bliptag-463899439 {\*\blipuid 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\par\pard\plain\sb264\cf1\f51\fs20\ql Twitter: https://twitter.com/akebiatx\par\pard\plain\sb264\cf1\f51\fs20\ql The following communication was posted on June\~28, 2018 by Akebia at www.linkedin.com:\par\pard\plain\cf1\f51\fs24\ql \~\par\ql{\*\shppict{\pict\pngblip\picw347\pich253\picscalex75\picscaley75\bliptag-463899439 {\*\blipuid 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