SEC FORM 4 SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
Smith Cynthia

(Last) (First) (Middle)
C/O AKEBIA THERAPEUTICS, INC
245 FIRST STREET

(Street)
CAMBRIDGE MA 02142

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
Akebia Therapeutics, Inc. [ AKBA ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
Officer (give title below) Other (specify below)
3. Date of Earliest Transaction (Month/Day/Year)
06/06/2019
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 06/06/2019 A 13,700(1) A $0.00 13,700 D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to buy) $4.23 06/06/2019 A 20,100(2) 06/06/2020 06/06/2029 Common Stock 20,100 $0.00 20,100 D
Explanation of Responses:
1. The restricted stock units were granted by the Issuer pursuant to its 2014 Incentive Plan, as amended, as provided by the Issuer's Amended and Restated Non-Employee Director Compensation Program (the "RSUs"). 100% of the RSUs will vest on the first anniversary of the grant date, subject to the Reporting Person's continued service to the Issuer.
2. Represents an option to purchase shares of the Issuer's common stock granted by the Issuer pursuant to its 2014 Incentive Plan, as amended, as provided by the Issuer's Amended and Restated Non-Employee Director Compensation Program (the "Stock Option"). 100% of the Stock Option will vest and become exercisable on the first anniversary of the grant date, subject to the Reporting Person's continued service to the Issuer.
Remarks:
/s/ Nicole R. Hadas, attorney-in-fact for Cynthia Smith 06/10/2019
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
POWER OF ATTORNEY
 
            Know all by these present, that the
undersigned hereby constitutes and appoints
each of John P. Butler,Jason Amello, Nicole R. 
Hadas, and Andrea Paul signing singly, as  the undersigned's 
true and lawful attorney-in-fact to:
 
(1)        prepare, execute in the undersigned's 
name and on the undersigned's behalf, and submit
to the U.S. Securities and Exchange Commission
(the "SEC") a Form ID, including amendments
 thereto,and any other documents necessary or
appropriate to obtain codes and passwords enabling
the undersigned to make electronic filings with
the SEC of reports required by Section 16(a) 
of the Securities Exchange Act of 1934 or any 
rule orregulation of the SEC;
 
            (2)        execute for and on behalf
 of the undersigned, in the undersigned's 
capacity as an officer and/or director or 
shareholder of Akebia Therapeutics, Inc.
the "Company"),Forms3, 4 and 5 in accordance
with Section 16(a) of the Securities
Exchange Act of 1934, as 
amended (the "Act"), and the rules thereunder;
 
            (3)        do and perform any and all 
acts for and on behalf of the undersigned which 
may be necessary or desirable to complete and 
execute any such Form 3, 4 or 5 and timely file
such form with the United States Securities and
Exchange Commission and any stock exchange
 or
similar authority; and
 
            (4)        take any other action
of any type whatsoever in connection with
the foregoing which, in the opinion of 
such attorney-in-fact, may be of benefit to,
in the best interest of, or legally 
required by, the undersigned, it being understood 
hat the documents executed by such attorney-in-fact
on behalf of the undersigned pursuant to this Power
of Attorneyshall be in such form and shall contain 
such terms and conditions as such attorney-in-fact
may approve in such attorney-in-fact's
discretion.
 
            The undersigned hereby grants to each 
attorney-in-factfull power and authority to do
and perform any and every act and thing whatsoever
requisite, necessary or proper to be done in the
exercise of any of the rights and powers herein 
granted, as fully to all intents and purposes as 
the undersigned might or could do if personally 
present, with full power ofsubstitution or 
revocation, hereby ratifying and confirming all 
the acts such attorney-in-fact shall lawfully do 
or cause to be done by virtue of this power of 
attorney and the rights and powers herein granted.  
The undersigned acknowledges that each of the 
foregoing attorneys-in-fact, in serving in such 
capacity at the request of the undersigned,
is not assuming any of the undersigned's 
responsibilities to comply with Section 16 of
the Act.
 
            This Power of Attorney shall remain 
in full force  and effect until the undersigned
is no longer required to file
Forms 3, 4 and 5 with respect to the undersigned's
holdings of and transactions in securities issued
by the Company, unless earlier revoked by the
undersigned in a signed writing delivered
to each of the foregoing attorneys-in-fact.
 

IN WITNESS WHEREOF, the undersigned has 
caused this Power of Attorney to be 
executed as of August 27, 2018.
 
By: /s/Cynthia Smith
Name: Cynthia Smith